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23-Hydroxybetulinic Acid Standard (≥98% HPLC) | CAS 85999-40-2
23-Hydroxybetulinic Acid (CAS: 85999-40-2) is a bioactive triterpenoid isolated from natural sources like Pulsatilla chinensis, renowned for its potent antitumor properties. With molecular formula C??H??O? and high purity (≥98% HPLC-verified), this compound serves as a critical reference standard in oncology and pharmacology research.
Product Name :
23-Hydroxybetulinic AcidCAS No. :
85999-40-2Appearance :
Fine White PowderSpecification :
98%CAS No.: 85999-40-2
Molecular Formula: C??H??O?
Molecular Weight: 472.70
Next-Gen Anticancer & Antidiabetic Triterpenoid
≥98% Pure: Off-white crystalline powder (Pharma Grade)
Mechanism-Validated Benefits:
Metastasis Suppressor: Inhibits MMP-9/FAK/Src pathways.
Antidiabetic Activity: Enhances insulin sensitivity.
Antiviral Potency: 3.7x stronger HIV-1 protease inhibition vs. betulinic acid.
Neuroprotection: Reduces Aβ plaque formation in Alzheimer’s models.
| Parameter | Detail |
|---|---|
| Purity | ≥98% (HPLC-ELSD) |
| Identification | ¹H/¹³C-NMR, Mass |
| Solubility | Soluble in DMSO, methanol; sparingly soluble in water (0.02 g/L at 25°C) |
| Melting Point | 226-228°C |
| Specific Rotation | +15° (c=0.1, pyridine) |
| Storage | 2-8°C (vacuum-sealed, amber vials; <0.1% O?) |
| Shelf Life | 24 months |
| Industry | Use Cases |
|---|---|
| Pharmaceuticals | - Antimetastatic drug leads (Phase II preclinical) - Type 2 diabetes therapeutics |
| Cosmeceuticals | - Anti-glycation creams (prevents AGE formation) - Melanogenesis inhibitor for brightening serums |
| Nutraceuticals | - Glucose metabolism support blends - Nootropic stacks for cognitive decline |
| Veterinary | - Equine metabolic syndrome management - Canine cognitive dysfunction supplements |
Enhanced Bioactivity: 2.1x greater apoptosis induction in drug-resistant cancers vs. betulinic acid.
Dual Targeting: Simultaneously modulates insulin signaling + cancer metastasis pathways.
Patent-Pending Delivery: Lyophilized nanoparticles.
Eco-Extraction: Closed-loop bioreactor synthesis from Betula platyphylla.
Bulk: 250 g/vacuum aluminum canisters (nitrogen flushed)
Samples: 25 mg, 100 mg in argon-filled HPLC vials
Stability: 98.2% purity retention after 18 months (2-8°C, desiccated)
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